What is Nicotine?
Nicotine is a SoulSeek client written in Python, based on the PySoulSeek project by Alexander Kanavin. It features, among other things, a completely rewritten graphical user interface which uses the PyGTK-2 toolkit and a less strict user request policy.

Features
Nicotine is a feature complete client for the SoulSeek filesharing network. You can use it to upload, download, search and chat. You can keep a "buddy" list and basically everything else a SoulSeek client is supposed to do. If you are familliar with PySoulSeek, you'll probably notice a striking resemblance in appearance. More info: Daelstorm's Nicotine Propaganda page.